Discovering Dendritic Cell Therapy
Dendritic cell based immunotherapy was first approved in 2010 in the United States as a vaccination cancer therapy for treating prostate cancer. Since then, there have been over 4,500 studies published on patients treated with this cancer vaccine. In studies, dendritic cell cancer treatment has been found to provide therapeutic and protective antitumor immunities. Clinical trials for cancer patients with melanoma, glioma, and non-Hodgkin’s lymphoma show promising antitumor results.
How Does Dendritic Cell Therapy & Vaccine Treatment Work
Dendritic cell (DC) vaccine treatment is a unique form of immunotherapy that has become more relevant among cancer patients. Autologous dendritic cells are rare leukocytes, a type of cell that plays a role in signaling the body’s immune system. The Dendritic cell is the most potent type of antigen presenting cell that is vital to proliferate T-lymphocyte, also known as T Cells. Antigen helps the body trigger an immune response. By activating T cells, dendritic cells help to promote antitumor immunity . These immune cells can help prevent the onset of cancer by suppressing tumor cell growth rates.
Dendritic cell therapy works by isolating dendritic cells with tumor antigen-loaded mature dendritic cells and administering them as a cellular, therapeutic vaccine. The process of performing DC therapy includes:
- Simple blood draw.
- Filtering of monocyte cells from peripheral blood and then loading it with tumor-associated antigens (TAA).
- Dendritic cell vaccination is then administered to the patient to attack tumour cells by activating T Cells in the lymph node(s).
Administrating DC therapy in a combination therapy with conventional cancer treatments such as chemotherapy and radiotherapy can serve as a promising treatment plan to improve its efficacy.
How Is Dendritic Cell Therapy Administered?
Dendritic Cell therapy can be injected intravenously, intramuscularly, intradermally, or directly into the tumor. Intervals for injection frequency of the DC vaccine can range from days to months to adapt an immune response. Consult with your doctor to determine the best mode of administration, dosage, and frequency of cancer immunotherapy based on your personal health needs.
Additional Questions? Call Immunity Therapy Center today and get started on your path towards recovery!
- “Optimizing Dendritic Cell-Based Approaches for Cancer Immunotherapy” ( Datta, Jashodeep; Terhune, Julia H.; Lowenfeld, Lea; Cintolo, Jessica A.; Xu, Shuwen; Roses, Robert E.; Czerniecki, Brian J.) : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257036/
- “ISOLATION AND GENERATION OF HUMAN DENDRITIC CELLS” by Smita Nair, Thomas Tedder, Gerald E. Archer: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559332/
- “Manufacturing Dendritic Cells for Immunotherapy: Monocyte” by : https://www.cell.com/molecular-therapy-family/methods/fulltext/S2329-0501(20)30008-5
At Immunity Therapy Center, our goal is to provide objective, updated, and research-based information on all health-related topics. This article is based on scientific research and/or other scientific articles. All information has been fact-checked and reviewed by Dr. Carlos Bautista, a Board Certified Medical Doctor at Immunity Therapy Center. All information published on the site must undergo an extensive review process to ensure accuracy. This article contains trusted sources with all references hyperlinked for the reader's visibility.
Customized Care For the Body And The Mind
Discuss Your Custom Alternative Treatment Plan With Our Team Today
Hear from Our Patients
Jack was diagnosed with Stage 4 prostate cancer and, as a result, was living his life in tremendous amounts of pain. It was Jack’s third time getting diagnosed with prostate cancer. Jack’s conventional doctor had put him through chemotherapy and other treatments but had begun to give up, telling Jack that his days were numbered. […]
Maria Petulla was diagnosed with Stage 4 breast cancer. Maria’s life was affected by the cancer; she became partially disabled and was living her life in a tremendous amount of pain. The cancer was taking over her life. After waking up one day and feeling the pain spread to her face, Maria knew that she […]
Robert Gray from Ontario, Canada has been battling stage 4 neuroendocrine carcinoid cancer. He came to ITC looking for a solution to shrink and eliminate his tumors. He found a kind and caring team of doctors at ITC that could focus on his case. Dr. Bautista brought knowledge and understanding to his case and helped […]
Alexandria, a United States resident, was diagnosed with Mantle Cell Lymphoma in March. The disease came very suddenly. After living a very active lifestyle, she could no longer walk and took a turn for the worst. She knew that she had to receive quality care fast if she was going to recover. When she met […]
In 2015, Pamela was diagnosed with Stage 2 Breast Cancer that escalated into Stage Four Breast Cancer. Along with her cancer, she also was dealing with infection and swelling on her chest and arm. After hearing about the success of integrative medicine over a conventional method, she knew that she wanted to start her journey […]
In 2019, Alberto was diagnosed with Prostate Cancer along with Pelvic Bone Metastasis. After attempting to treat his cancer from the mountains of Mexico, a family member came across Immunity Therapy Center and Alberto and his family decided it would be the best route forward. He began his journey at Immunity Therapy Center in late […]
“The approach they take here is to help the body, to strengthen the immune system, and to stimulate it, so that the body itself fights the disease” In 2018, Joseph Turkington’s health started to deteriorate. A usually healthy person, he began to have pains in his stomach area, pains so bad that he eventually decided […]
“ITC offers so many different therapies and none of them are painful at all. During my time at ITC my quality of life was not taken away from me [unlike with Chemotherapy] and my lymphoma shrank drastically” In 2016, Fouad Youssef discovered he had a lymphoma the size of his thumb knuckle under his arm. […]
When Xiao was diagnosed with stage 4 Lymphoma her pain was so bad she classified it at a level 10 every single day. After just a few days at Immunity Therapy Center her pain dropped to a 5, and after a full week she didn’t even need to take her pain medicine anymore. Xiao encourages […]
Prior to being diagnosed with Hodgkin Lymphoma, Melissa Porter lead a very healthy lifestyle. While traveling in Costa Rica she found a lump in her right underarm that was found to be Cancerous. When Melissa returned home she researched a variety of alternative treatment options and after being told about Immunity Therapy Center by her […]