Cushing Syndrome Support

Cushing syndrome (hypercortisolism) occurs when the body is exposed to high levels of the hormone cortisol for a prolonged period of time. The most common cause of Cushing syndrome is the use of oral corticosteroid medication, but it may also occur when the body overproduces cortisol due to malfunction or disease of the adrenal glands.

Typical signs of Cushing syndrome include a fatty hump between the shoulders, a rounding of the face, and pink or purple stretch marks on the skin. Cushing syndrome can lead to high blood pressure, bone loss, and in rare cases, diabetes.

Cushing syndrome symptoms vary greatly, and are often different in men and women. Symptoms include:

  • Weight gain and fatty tissue deposits, particularly in midsection, upper back, face (moon face), and between the shoulders (buffalo hump)
  • Pink or purple stretch marks (striae) on abdomen, thighs, breasts, and arms
  • Thin, fragile skin that bruises easily
  • Slow healing of cuts, insect bites, and infection
  • Acne
  • Fatigue
  • Muscle weakness
  • Depression, anxiety, and irritability
  • Loss of emotional control
  • Cognitive difficulties
  • New or worsened high blood pressure
  • Glucose intolerance (may lead to diabetes)
  • Headache
  • Bone loss (leading to fractures over time)

Cushing syndrome symptoms specific to women include:

  • Thicker or more visible body and facial hair (hirsutism)
  • Irregular or absent menstrual periods

Cushing syndrome symptoms specific to men include:

  • Decreased libido
  • Decreased fertility
  • Erectile dysfunction